Abdominal bloating: an under-recognized endometriosis symptom. Gastrointestinal symptoms among endometriosis patients-a case-cohort study. One study found that both current and previous GnRH use was associated with more severe gastrointestinal symptoms, including bloating.Įk M, Roth B, Ekström P, et al. GnRH analogs: GnRH analogs are a group of medications that may be prescribed to suppress endometriosis symptoms in the short term by inducing false menopause.One study found that current opioid use was associated with more severe gastrointestinal symptoms, including bloating. Opioids: Opioids are strong painkillers that may be prescribed in some cases for endometriosis-related pain.This condition can cause significant bloating, diarrhea, and constipation. Small intestine bacteria overgrowth (SIBO): SIBO is more common among people with endometriosis.This altered microbiome may contribute to bloating, though it is not entirely clear why this is the case. Altered gut microbiome: One recent study found that people with endometriosis have less gut bacteria diversity than healthy controls.In some cases, this may even obstruct or narrow the intestines, causing cause pain and bloating. Adhesions: Endometriosis can cause adhesions (scar tissue) to form, essentially tethering or "gluing" organs, such as the large intestine, in place.This inflammation can irritate the organs and tissues in the abdomen, and even slow intestinal motility (how fast stool travels), all leading to bloating. Inflammation: Endometriosis lesions release large amounts of inflammatory mediators, including prostaglandins, tumor necrosis factor, nerve growth factor, interleukins, and vascular endothelial growth factor.
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